Efficacy of Intravenous Ferric Gluconate on Dialysis Patients

The research study investigated the efficacy of intravenous (IV) ferric gluconate to patients undergoing hemodialysis during the eight-week period. The research is based on numerical parameters such as age, patient on hemodialysis for more than 90 days, and several laboratory values. The researchers utilized laboratory values namely ferric gluconate, transferrin saturation (TSAT), white blood cells, MCV, MCH, Serum Albumin, and C-reactive protein. Ferritin is used as the major laboratory test to assess iron stores in dialysis patients in this research study.

Based on the parameters mentioned, it can be gathered that the research study is quantitative in nature. In fact, the primary objectives of the study are to compare the difference between the control and experimental groups from baseline to week 8 in hemoglobin count. The secondary objectives consist of a comparison between the control (no treatment) and experimental (with treatment) groups including their laboratory findings of CFB in TSAT, serum ferritin, and C-reactive protein.

The laboratory value of retoculocyte hemoglobin content found in the primary objective is aimed to measure the efficacy of serum gluconate while the laboratory values found in the secondary objective were mainly to measure the safety of patients in terms of levels of inflammation. Moreover, one of the qualifying data is the selection of patients who receive epoetin dosage while on hemodialysis. Thus, a quantitative approach is highly suitable to determine the efficacy of IV serum ferritin to patients on hemodialysis as well as determining how patients respond and cope upon administration of IV serum ferritin.

A qualitative approach defeats the purpose of the research study given the manipulation of the study variables and the use control and experimental groups. In conclusion, the research achieved its aim by confirming that ferric gluconate is highly efficacious in anemic patients on hemodialysis. The findings are backed up with solid, laboratory findings that show an increased level of serum ferritin and TSAT.